Human IL-1R2/IL-1 RII/CD121b Protein (LTP10973)

Product Name
Human IL-1R2/IL-1 RII/CD121b Protein (LTP10973)
Catalog Number
LTP10973
Quantity
100ug
Price
$316 In stock
Background
Interleukin (IL)-1 has been reported to be involved in the development of tuberculosis (TB). IL1R1 and IL1R2 encode a cytokine receptor that belongs to the IL-1 receptor family.IL1R2 (Interleukin 1 Receptor Type 2) is a Protein Coding gene. Diseases associated with IL1R2 include Endometriosis and Mastitis. Among its related pathways are Hematopoietic cell lineage and IL-1 signaling pathway. Gene Ontology (GO) annotations related to this gene include interleukin-1 receptor activity and interleukin-1, type II, blocking receptor activity.
Description
Recombinant Human IL-1R2/IL-1 RII/CD121b Protein is expressed from Expi293 with His tag at the C-terminal. It contains Phe14-Glu343.
Target
IL-1R2/IL-1 RII/CD121b
Species
Human
Gene/Protein ID
NP_004624.1
Exact Sequence
Phe14-Glu343
Molecular Weight
The protein has a predicted MW of 38.9 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human IL-1R2, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 15.1ng/ml determined by ELISA. See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human IL-1R2/IL-1 RII/CD121b Protein (LTP10973)
  • 5 Units in Stock

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