Human IgG4 Fc Protein (LTP11022)

Product Name
Human IgG4 Fc Protein (LTP11022)
Catalog Number
LTP11022
Quantity
100ug
Price
$113 In stock
Background
It is known as a IgG4-related disease and its differentiation is based on the analysis of IgG4 levels in the affected tissues. The IgG4-related disease is considered to be a generalized pathological process involving a wide spectrum of various disorders that may affect distant organs.
Description
Recombinant Human IgG4 Fc Protein is expressed from Expi293 without tag. It contains Glu99-Gly326.
Target
IgG4 Fc
Species
Human
Gene/Protein ID
P01861
Exact Sequence
Glu99-Gly326
Molecular Weight
The protein has a predicted MW of 25.8 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on the Tris-Bis PAGE result.
Activity
The affinity constant of 1.365 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
No Tag
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human IgG4 Fc Protein (LTP11022)
  • 5 Units in Stock
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