Human IGFBP-7 Protein (LTP11038)

Product Name
Human IGFBP-7 Protein (LTP11038)
Catalog Number
LTP11038
Quantity
100ug
Price
$305 In stock
Background
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
Description
Recombinant Human IGFBP-7 Protein Protein is expressed from Expi293 with His tag at the N-terminal. It contains Ser27-Leu282.
Target
IGFBP-7
Species
Human
Gene/Protein ID
Q16270
Exact Sequence
Ser27-Leu282
Molecular Weight
The protein has a predicted MW of 27.5 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human IGFBP-7, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 0.74ug/ml determined by ELISA. See testing image for detail.
Tag
N-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human IGFBP-7 Protein (LTP11038)
  • 5 Units in Stock
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