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| Human IFN alpha/beta R2 Protein (LTP10572) |
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| LTP10572 |
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| 100ug |
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$339 In stock |
| Although interferon (IFN)-? is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-?-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-?'s effects on DCs are mediated through miRNAs as well. |
| Recombinant Human IFN alpha/beta R2 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ile27-Lys243. |
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| IFN alpha/beta R2 |
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| Human |
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| P48551-2 |
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| Ile27-Lys243 |
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| The protein has a predicted MW of 25.8 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on the Tris-Bis PAGE result. |
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| The affinity constant of 11.90 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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