| Human IFN alpha/beta R2 Protein (LTP10572) |
| LTP10572 |
| 100ug |
|
$339 In stock |
| Although interferon (IFN)-? is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-?-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-?'s effects on DCs are mediated through miRNAs as well. |
| Recombinant Human IFN alpha/beta R2 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ile27-Lys243. |
| IFN alpha/beta R2 |
| Human |
| P48551-2 |
| Ile27-Lys243 |
| The protein has a predicted MW of 25.8 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on the Tris-Bis PAGE result. |
| The affinity constant of 11.90 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
| C-His |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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