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| Human HVEM/TNFRSF14 Protein (LTP10778) |
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| LTP10778 |
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| 100ug |
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$406 In stock |
| Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily. Two TNF superfamily ligands lymphotoxin ? (TNF-?) and LIGHT (TNFSF14) are identified as cellular ligands for HVEM and initiate the positive signaling. |
| Recombinant Human HVEM/TNFRSF14 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Leu39-Val202. |
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| HVEM/TNFRSF14 |
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| Human |
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| Q92956-1 |
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| Leu39-Val202 |
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| The protein has a predicted MW of 44.3 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human BTLA, His Tag at 2ug/ml (100ul/Well). Dose response curve for Human HVEM, hFc Tag with the EC50 of 32.6ng/ml determined by ELISA (QC Test). The affinity constant of 1.2uM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| C-hFc |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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