Human CD2/SRBC Protein (LTP11089)

Product Name
Human CD2/SRBC Protein (LTP11089)
Catalog Number
LTP11089
Quantity
100ug
Price
$450 In stock
Background
The CD2 family of receptors is evolutionarily conserved and widely expressed on cells within the hematopoietic compartment. In recent years several new members have been identified with important roles in the immune system. CD2 family members regulate natural killer (NK) cell lytic activity and inflammatory cytokine production when engaged by ligands on tumor cells.
Description
Recombinant Human CD2/SRBC Protein is expressed from Expi293 with His tag at the C-terminal. It contains Lys25-Asp209.
Target
CD2/SRBC
Species
Human
Gene/Protein ID
P06729
Exact Sequence
Lys25-Asp209
Molecular Weight
The protein has a predicted MW of 22.3 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on the Tris-Bis PAGE result.
Activity
The affinity constant of 15.48 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CD2/SRBC Protein (LTP11089)
  • 5 Units in Stock

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