Human CD161 Protein (LTP10433)

Product Name
Human CD161 Protein (LTP10433)
Catalog Number
LTP10433
Quantity
100ug
Price
$519 In stock
Background
CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment.
Description
Recombinant Human CD161 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gln67-Ser225.
Target
CD161
Species
Human
Gene/Protein ID
Q12918-1
Exact Sequence
Gln67-Ser225
Molecular Weight
The protein has a predicted MW of 19.6 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human CD161, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CD161 Antibody, hFc Tag with the EC50 of 11.4ng/ml determined by ELISA (QC Test). The affinity constant of 78.8 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CD161 Protein (LTP10433)
  • 5 Units in Stock

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