Human CD160 Protein (LTP10887)

Product Name
Human CD160 Protein (LTP10887)
Catalog Number
LTP10887
Quantity
100ug
Price
$360 In stock
Background
CD160 (also Natural killer cell receptor BY55) is a 27 ? 30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. CD160 antigenis a receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells.
Description
Recombinant Human CD160 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Gly25-Leu158.
Target
CD160
Species
Human
Gene/Protein ID
O95971
Exact Sequence
Gly25-Leu158
Molecular Weight
The protein has a predicted MW of 17.7 kDa. Due to glycosylation, the protein migrates to 27-33 kDa based on the Tris-Bis PAGE result.
Activity
The affinity constant of 1.2uM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
C-His-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CD160 Protein (LTP10887)
  • 5 Units in Stock

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