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| Human Adiponectin/Acrp30 Protein (LTP10445) |
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| LTP10445 |
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| 100ug |
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$339 In stock |
| Adiponectin, also known as Acrp30, is an adipocyte-derived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation.Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. |
| Recombinant Human Adiponectin/Acrp30 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Glu19-Asn244. |
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| Adiponectin/Acrp30 |
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| Human |
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| Q15848 |
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| Glu19-Asn244 |
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| The protein has a predicted MW of 51.2 kDa. Due to glycosylation, the protein migrates to 52-70 kDa based on the Tris-Bis PAGE result. |
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| 0 |
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| C-hFc |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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