Product Name | Gly3-vc-PAB-MMAE |
Product Quantity | 2 mg |
Catalog Number | 35815 |
Category | Peptide |
Sequence | Gly-Gly-Gly-Ahx-vc-PAB-MMAE |
Purity | >95% |
Catalog Number: 35815 | 35815, Gly3-vc-PAB-MMAE: Gly-Gly-Gly-Ahx-vc-PAB-MMAE |
Peptide Info | Linker-Toxin SET, this set is made by Monomethyl auristatin E (MMAE) conjugated to the lysosomally cleavable Gly3-vc-PAB linker. MMAE, a potent tubulin inhibitor, is a toxin payload in the antibody-drug conjugate. Molecular Formula: C83H132N16O21S; Formula Weight: 1722.12 |
Scientific Background | Gly3-vc-PAB-MMAE is a 3-residue synthetic peptide with the sequence Gly-Gly-Gly. an Ahx spacer separates the peptide from an attached label or affinity handle. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
