| GILGFVFTL is a 9-amino acid peptide derived from the Influenza A matrix protein 1 (M1), specifically from residues 58-66. This epitope is recognized by CD8+ cytotoxic T lymphocytes (CTLs) and is presented by the human major histocompatibility complex (MHC) class I molecule HLA-A*02:01. Due to its immunodominant nature, GILGFVFTL is extensively utilized in immunological research, particularly in assays assessing T-cell responses to influenza infection.
GILGFVFTL is a valuable tool in immunological research, offering robust applications such as: CD8+ T-Cell Stimulation: Used in T-cell assays, including ELISPOT, intracellular cytokine staining (ICS), cytotoxicity, and proliferation assays. Antigen Loading: Compatible with dextramers/tetramers for antibody production. Research and Development: Assists in mapping T-cell epitopes, immune monitoring, and vaccine development.
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