Product Name | Gastrin Releasing Peptide,human |
Product Quantity | 5mg |
Catalog Number | LT1473 |
Molecular Weight | 2859.4 |
Formula | C130H204N38O31S2 |
Sequence | Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2 |
Product Description | Gastrin releasing peptide (GRP) is released by the G cells of the stomach after they receive a stimulus from the post-ganglionic fibres of the vagus nerve. Gastrin-releasing peptide is an important growth-modulating factor in developing lung epithelium. It is used as a tumor marker in the diagnosis of small-cell lung carcinoma, since it is known to be produced by these cancer cells. |
Scientific Background | Gastrin Releasing Peptide,human is a 27-residue synthetic peptide with the sequence Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met. C-terminal amidation removes the terminal carboxylate charge. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
