Product Name | FMRF amide Molluscan Cardioexcitatory Peptide |
Product Quantity | 10mg |
Catalog Number | LT1446 |
Molecular Weight | 598.76 |
Formula | C29H42N8O4S |
Sequence | Phe-Met-Arg-Phe-NH2 |
Product Description | Phe-Met-Arg-Phe (FMRF amide) is a neurotransmitter peptide which increases outward K+ currents and promotes dephosphorylation of many phosphoproteins in Aplysia sensory neurons. It is a cardioexcitatory substance from Macrocallista nimbosa (sun-ray clam), has physiological activities on the heart like augmenting, inducing and regularizing cardiac contraction. |
Scientific Background | FMRF amide Molluscan Cardioexcitatory Peptide is a 4-residue synthetic peptide with the sequence Phe-Met-Arg-Phe. C-terminal amidation removes the terminal carboxylate charge. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |