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DSPE-PEG2000-HA Tag Peptide is based on the canonical influenza hemagglutinin epitope tag YPYDVPDYA, commonly known as the HA tag. The construct includes an N-terminal cysteine/GGGG spacer and a DSPE-PEG2000 lipid conjugation configuration.
HA Epitope Tag
The HA tag is a compact nine-amino-acid peptide derived from influenza hemagglutinin. It is widely used for detection, immunoprecipitation, affinity capture, and localization of recombinant proteins because many well-characterized anti-HA antibodies are available.
DSPE-PEG2000-HA Configuration
The N-terminal cysteine allows maleimide coupling to DSPE-PEG2000. DSPE provides a phospholipid anchor and PEG2000 provides a hydrophilic spacer, making this format useful for displaying an HA epitope on liposomes, lipid nanoparticles, micelles, or model membranes.
- Anti-HA antibody binding
- Lipid-particle surface labeling
- Immunocapture controls
- Membrane display studies
References
Thermo Fisher Scientific Overview of Epitope Tagging. Technical reference.
Public source / publication Related LifeTein Services
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Research Use Only. Not for human, diagnostic, clinical, or therapeutic use.
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