Product Name | [Des-Ser1] Cerebellin |
Product Quantity | 5mg |
Catalog Number | LT0540 |
Molecular Weight | 1545.73 |
Formula | C66H108N22O21 |
Sequence | Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His |
Product Description | Cerebellin, a 16-amino acid peptide originally isolated from rat cerebellum, is widely distributed in the central nervous system. Cerebellin exerts neuromodulatory functions. Directly stimulates norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. |
Scientific Background | [Des-Ser1] Cerebellin is a 15-residue synthetic peptide with the sequence Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
