| Cynomolgus/Rhesus macaque B7-H4 Protein (LTP10112) |
| LTP10112 |
| 100ug |
|
$406 In stock |
| B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease statusĀ . |
| Recombinant Cynomolgus/Rhesus macaque B7-H4 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Phe29-Ala258. |
| B7-H4 |
| Cynomolgus/Rhesus macaque |
| A0A2K5U6P5 / F7B770 |
| Phe29-Ala258 |
| The protein has a predicted MW of 26.41 kDa. Due to glycosylation, the protein migrates to 48-63 kDa based on the Tris-Bis PAGE result. |
| Immobilized Cynomolgus/Rhesus macaque B7-H4, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-B7-H4 Antibody, hFc Tag with the EC50 of 12.8ng/ml determined by ELISA. See testing image for detail. |
| C-His |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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