|
| Cynomolgus uPAR/PLAUR Protein (LTP10065) |
|
| LTP10065 |
|
| 100ug |
|
|
$339 In stock |
| The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR. |
| Recombinant Cynomolgus uPAR/PLAUR Protein is expressed from Expi293 with His tag at the C-terminal. It contains Leu23-Gly305. |
|
| uPAR/PLAUR |
|
| Cynomolgus |
|
| Q9GK78 |
|
| Leu23-Gly305 |
|
| The protein has a predicted MW of 32.69 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result. |
|
| Immobilized Cynomolgus uPAR, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human PLAU, His Tag with the EC50 of 13.8ng/ml determined by ELISA (QC Test). The affinity constant of 0.033 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
|
| C-His |
|
| Expi293 |
|
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
|
| Less than 1EU per ug by the LAL method. |
|
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
|
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
| Shipped at ambient temperature. |
|
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
|
|  |
