Cynomolgus GAS6 Protein (LTP10104)

Product Name
Cynomolgus GAS6 Protein (LTP10104)
Catalog Number
LTP10104
Quantity
100ug
Price
$473 In stock
Background
Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
Description
Recombinant Cynomolgus GAS6 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ala31-Ala637.
Target
GAS6
Species
Cynomolgus
Gene/Protein ID
A0A2K5VGX7
Exact Sequence
Ala31-Ala637
Molecular Weight
The protein has a predicted MW of 68.55 kDa. Due to glycosylation, the protein migrates to 69-74 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Cynomolgus GAS6, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-Gas6 Antibody, hFc Tag with the EC50 of 26.1ng/ml determined by ELISA (QC Test). The affinity constant of 1.70 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Cynomolgus GAS6 Protein (LTP10104)
  • 5 Units in Stock

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