Cynomolgus DLL3 Protein (LTP10303)

Product Name
Cynomolgus DLL3 Protein (LTP10303)
Catalog Number
LTP10303
Quantity
100ug
Price
$1126 In stock
Background
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
Description
Recombinant Cynomolgus DLL3 Protein is expressed from Expi293 with His tag at the N-terminal. It contains Ala27-Arg490.
Target
DLL3
Species
Cynomolgus
Gene/Protein ID
A0A2K5WSR4
Exact Sequence
Ala27-Arg490
Molecular Weight
The protein has a predicted MW of 51 kDa. Due to glycosylation, the protein migrates to 52-55 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Cynomolgus DLL3, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA. See testing image for detail.
Tag
N-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in 20mM PB, 200mM NaCl (pH 8.0). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Cynomolgus DLL3 Protein (LTP10303)
  • 5 Units in Stock
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