Product Name | Corazonin, American Cockroach, Periplaneta americana |
Product Quantity | 5mg |
Catalog Number | LT1273 |
Molecular Weight | 1369.49 |
Formula | C62H86N18O19 |
Sequence | Pyr-Thr-Phe-Gln-Tyr-Ser-Arg-Gly-Trp-Thr-Asn-NH2 |
Product Description | Corazonin is a highly conserved and cardioaccelerating peptide, which has been isolated from the corpus cardiacum of the American cockroach, Periplaneta americana. It is the most potent insect cardioactive neuropeptide.Corazonin (from corazon, Spanish for heart) is produced by lateral brain neurosecretory cells projecting to the corpora cardiaca-corpora allata complex and in neurons of the ventral nerve cord. |
Scientific Background | Corazonin, American Cockroach, Periplaneta americana is a 10-residue synthetic peptide with the sequence Thr-Phe-Gln-Tyr-Ser-Arg-Gly-Trp-Thr-Asn. C-terminal amidation removes the terminal carboxylate charge. The sequence contains 3 aromatic residues that can contribute to hydrophobic or aromatic interactions. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
