Braftide TRHVNILLFM

Product Name
Braftide TRHVNILLFM
Product Quantity
4mg
Catalog Number
67630
Sequence
TRHVNILLFM;
Purity
>95%
Name
Braftide, TRHVNILLFM
Product Description
Braftide is a 10-mer peptide TRHVNILLFM. Braftide disrupts BRAF dimers and inhibits BRAF kinase activity. Braftide causes degradation of BRAF leading to destabilized MAPK complexes. Braftide synergizes with ATP-competitive inhibitors like Dabrafenib to mitigate paradoxical MAPK activation and downregulate MAPK signaling.
Scientific Background

Braftide TRHVNILLFM is a 10-residue synthetic peptide with the sequence Thr-Arg-His-Val-Asn-Ile-Leu-Leu-Phe-Met. The sequence has a relatively high hydrophobic-residue fraction that can influence aqueous solubility and surface adsorption. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence.

Research Applications
  • LC-MS/HPLC analytical method development
  • sequence-specific assay controls
Experimental Notes

Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions.

  • 5 Units in Stock
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$300.00

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