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| Biotinylated Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (LTP10092) |
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| LTP10092 |
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| 100ug |
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$900 In stock |
| ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling. |
| Recombinant Biotinylated Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Phe31-Val992(ITGAV) acidic tail&Gly27-Asp718(ITGB3) basic tail. |
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| ITGAV&ITGB3 |
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| Human |
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| P06756-1(ITGAV)&P05106-1(ITGB3) |
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| Phe31-Val992(ITGAV)acidic tail & Gly27-Asp718(ITGB3)basic tail |
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| The protein has a predicted MW of 114 kDa (ITGAV)&81.3 kDa (ITGB3). Due to glycosylation, the protein migrates to 90-145 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Anti-alpha V beta3 Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB3, His Tag with the EC50 of 54ng/ml determined by ELISA. See testing image for detail. |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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