Bactenecin, bovine

This a cyclic cationic dodecapeptide isolated from bovine neutrophil granules. It exhibits a significant antibacterial activity in vitro that is comparable to that of the defensins.

Bactenecin, bovine is a 14-residue synthetic peptide with the sequence Arg-Leu-Cys-Arg-Ile-Val-Val-Ile-Arg-Val-Cys-Arg-Cys-Cys. The sequence contains 4 cysteine residues, providing potential thiol/disulfide chemistry when the thiol is available; contains 0 Lys and 4 Arg residues, contributing cationic character. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence.

• thiol-selective conjugation or immobilization studies
• LC-MS/HPLC analytical method development
• sequence-specific assay controls

Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions.