| 5595 |
| Apamin CNCKAPETALCARRCQQH - NH2 (Disulfide bridge: 1 - 11, 3 - 15) |
| CNCKAPETALCARRCQQH, H-Cys¹-Asn-Cys³-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys¹¹-Ala-Arg-Arg-Cys15-Gln-Gln-His-NH (disulfide bonds: 1 - 11; 3 - 15); Formula: C79H131N31O24S4 |
| C-Terminal: Amidation, Disulfide Bridge: 1-11, 3-15 |
| 3mg |
| >95% |
| An 18-amino acid peptide from bee venom, a selective blocker of calcium activated potassium channels.Polypeptide neurotoxin known to pass through the blood-brain barrier. Blocks the AHP-type Ca2+-activated K+ channel; does not block the TEA and voltage-sensitive Ca2+-activated K+ channel. Reported to induce neurodegeneration of Purkinje cells in rat brain. Known to induce the secretion of prolactin in a dose-dependent manner. |
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