Adropin (34-76), Human/Mouse/Rat

Adropin(34-76) is the putative secreted, biologically active region of the 76-residue peptide encoded by the energy-homeostasis-associated ENHO gene. Experimental studies using synthetic adropin(34-76) have linked the peptide to regulation of glucose utilization, insulin signaling and metabolic flexibility in diet-induced obesity models. Later work showed effects on hepatic insulin-signaling pathways, endoplasmic-reticulum stress and glucose production.

• energy-homeostasis research
• glucose and lipid metabolism studies
• insulin-signaling research
• metabolic flexibility studies

This catalog form corresponds specifically to residues 34-76 rather than full-length adropin. The current LifeTein specification reports MW 4501.88 and ≥95% HPLC purity. Research findings from animal models should not be presented as established therapeutic effects in humans.

1. Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance
2. The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity