HIV-1 tat Protein Cys TAT (47-57)

Product Name
HIV-1 tat Protein Cys TAT (47-57)
Product Quantity
5mg

Product Description

This is the most characterized fragment of the HIV transactivator protein (TAT) CYGRKKRRQRR. This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis. Oligomers of the TAT(47-57) peptide compact plasmid DNA to nanometric particles and stabilize DNA towards nuclease degradation. At optimized vector compositions. these peptides mediated gene delivery to cells in culture 6-8-fold more efficiently than poly-L-arginine or the mutant TAT2-M1. The HIV-tat peptide YGRKKRRQRR is a powerful tool in biotechnology and medicine, primarily due to its cell-penetrating capabilities. Its applications range from genetic engineering in microalgae to enhancing drug delivery and protecting against UV-induced skin damage. The ongoing research into its uptake mechanisms and potential uses in various fields highlights its versatility and importance in scientific advancements.

Catalog Number
LT8115
Molecular Weight
1662
Formula
C64H118N32O14
Sequence
Cys-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg, CYGRKKRRQRR, amide
  • 2 Units in Stock

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$262.00

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