Product Name
Product Quantity
Catalog Number
Molecular Weight
Liraglutide is a full agonist of the GLP-1 receptor and shares 97% of its amino acid sequence identity with human GLP-1. The Lys 34 in GLP-1 was substituted for by an arginine and an N-e(y- Glu[N-a-hexadecanoyl]) residue and was attached to Lys 26. This lipid anchor causes strong albumin binding, which protects the peptide against degradation. Semaglutide’s structure differs from liraglutide in two places. The Glycine at position 2 is substituted with Aib (U) and this modification provides significant protection against enzymatic degradation by DPP-4. In addition, a modified fatty acid chain and the two PEG2 spacers turned out to be optimal for both in vitro and in vivo prolonged duration of action. In June 2021, the US Food and Drug Administration (FDA) approved semaglutide injection sold under the brand name Wegovy for long-term weight management in adults.
  • 10 Units in Stock

Ask a Question

Call for Price

Add to Cart:
LifeTein LifeTein provides custom peptide synthesis service, recombinant proteins, peptides, cytokines, custom antibody service and custom protein service. LifeTein is the world leader in fast peptide synthesis service with lab facility located in New Jersey USA. LifeTein Peptide 100 Randolph Road, Suite 2D, Somerset USA New Jersey 08873
Copyright © 2023 Powered by LifeTein