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| Mouse Fc gamma RIV/CD16-2 Protein (LTP10329) |
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| LTP10329 |
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| 100ug |
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$473 In stock |
| FcgammaRIV is a relatively new IgG Fc receptor (FcgammaR) that is reported to contribute to the pathogenesis of autoimmune diseases.FcgammaRIII and FcgammaRIV are each essential to trigger an FcRgamma-linker for activation of T-cell-dependent signal that drives C5a production in the Arthus reaction. A combined requirement for FcgammaRIII and FcgammaRIV in autoimmune injury, and identify the linker for activation of T cells adaptor as an integral component of linked FcgammaR and C5a anaphylatoxin receptor activation to generate inflammation. |
| Recombinant Mouse Fc gamma RIV/CD16-2 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gly21-Gln203. |
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| Fc gamma RIV/CD16-2 |
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| Mouse |
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| A0A0B4J1G0-1 |
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| Gly21-Gln203 |
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| The protein has a predicted MW of 22 kDa. Due to glycosylation, the protein migrates to 32-43 kDa based on the Tris-Bis PAGE result. |
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| The affinity constant of 146 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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