ADH5/GSNOR Rabbit mAb

Product Name
ADH5/GSNOR Rabbit mAb
Catalog Number
LTA24733
Quantity
100ul
Price
$750 In stock
Description
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Alias
FDH; ADHX; ADH-3; AMEDS; BMFS7; FALDH; GSNOR; GSH-FDH; HEL-S-60p
Keywords
128,sc-103375,sc-135338,ADH 3,ADH5,ADHX,Alcohol dehydrogenase 5,Alcohol dehydrogenase class 3,FALDH,FDH,GSH FDH,GSNOR,ADH-3,GSH-FDH,HEL-S-60p,alcohol dehydrogenase 5 (class III),chi polypeptide,alcohol dehydrogenase class-3,S-(hydroxymethyl)glutathione dehydrogenase,S-nitrosoglutathione reductase,alcohol dehydrogenase (class III),alcohol dehydrogenase class chi chain,alcohol dehydrogenase class-III,epididymis secretory sperm binding protein Li 60p,formaldehyde dehydrogenase,glutathione-dependent formaldehyde dehydrogenase,P11766,Alcohol Dehydrogenase 5 (Class III),Chi Polypeptide,Glutathione-Dependent Formaldehyde Dehydrogenase,S-(Hydroxymethyl)Glutathione Dehydrogenase,Alcohol Dehydrogenase Class Chi Chain,Alcohol Dehydrogenase Class-III,S-Nitrosoglutathione Reductase,Formaldehyde Dehydrogenase,Alcohol Dehydrogenase (Class III),Epididymis Secretory Sperm Binding Protein Li 60p,Alcohol Dehydrogenase Class-3,Alcohol Dehydrogenase 5,EC 1.1.1.284,EC 1.1.1.1,EC 1.1.1.-
Gene Template Species
Human
Gene/Protein ID
128
SWISS ID
P11766
Antigen Sequence
MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVVKI
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-374 of human ADH5/GSNOR (NP_000662.3).
Animal Source
Rabbit
Antibody Type
Affinity Purified Monoclonal IgG
Applications
WB, ELISA
Cross-Reactivity
Human, Mouse, Rat
Molecular Weight
40kDa
Recommended Dilution
WB,1:10000 - 1:40000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements.
Stability and Storage

Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.

Image
 ADH5/GSNOR Rabbit mAb

Western blot analysis of various lysates using ADH5/GSNOR Rabbit mAb (LTA24733) at 1:23000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 60s.

  • 4 Units in Stock

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