Human Claudin 18.2 Protein-VLP (LTP10686)

Product Name
Human Claudin 18.2 Protein-VLP (LTP10686)
Catalog Number
LTP10686
Quantity
100ug
Price
$1350 In stock
Background
Claudin18(CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells.CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants,CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.
Description
Full length Human Claudin 18.2 Protein-VLP is expressed from Expi293. It contains Met1-Val261.
Target
Claudin 18.2
Species
Human
Gene/Protein ID
P56856-2
Exact Sequence
Met1-Val261
Molecular Weight
The target protein has a predicted MW of 29 kDa.
Activity
Immobilized Human Claudin 18.2 VLP at 5ug/ml (100ul/Well). Dose response curve for Anti-Claudin 18.2 Antibody, hFc Tag with the EC50 of 9.8ng/ml determined by ELISA (QC Test). The affinity constant of 2.20 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
0
Express System
Expi293
Purity
> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.Notice: If you need it for immunization, Do Not use any adjuvant.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human Claudin 18.2 Protein-VLP (LTP10686)
  • 5 Units in Stock

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