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| TCPTP/PTPN2 Rabbit mAb |
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| LTA24736 |
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| 100ul |
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$750
In stock
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| The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. |
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| PTN2; PTPT; TCPTP; TC-PTP; TCELLPTP |
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| 5771,sc-102129,sc-135425,PTPN2,PTPT,TC PTP,TCELLPTP,TCPTP,PTN2,TC-PTP,protein tyrosine phosphatase,non-receptor type 2,tyrosine-protein phosphatase non-receptor type 2,T-cell protein tyrosine phosphatase,P17706,Protein Tyrosine Phosphatase,Non-Receptor Type 2,Tyrosine-Protein Phosphatase Non-Receptor Type 2,T-Cell Protein Tyrosine Phosphatase,T-Cell Protein-Tyrosine Phosphatase,EC 3.1.3.48 |
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| Human |
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| 5771 |
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| P17706-3 |
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| MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSERPRLTDT |
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| Recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human TCPTP/PTPN2 (NP_536348.1). |
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| Rabbit |
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| Affinity Purified Monoclonal IgG |
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| WB, ELISA |
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| Human, Mouse, Rat |
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| 48kDa |
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| WB,1:1000 - 1:6000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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| .jpg )
Western blot analysis of lysates from HeLa cells using TCPTP/PTPN2 Rabbit mAb (LTA24736) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 10s. |
