|
| TAP2 Rabbit mAb |
|
| LTA24796 |
|
| 100ul |
|
|
$750
In stock
|
|
| The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. |
|
| APT2; PSF2; ABC18; ABCB3; PSF-2; RING11; D6S217E |
|
| 6891,sc-11473,sc-11470,sc-25612,TAP2,ABC18,ABCB3,APT2,D6S217E,PSF-2,PSF2,RING11,transporter 2,ATP binding cassette subfamily B member,antigen peptide transporter 2,ABC transporter,MHC 2,ATP-binding cassette,sub-family B (MDR/TAP),member 3,peptide supply factor 2,peptide transporter PSF2,peptide transporter involved in antigen processing 2,really interesting new gene 11 protein,ABC (ATP binding cassette),Q03519,Transporter 2,ATP Binding Cassette Subfamily B Member,ATP-Binding Cassette,Sub-Family B (MDR/TAP),Peptide Transporter Involved In Antigen Processing 2,Really Interesting New Gene 11 Protein,Peptide Transporter PSF2,Peptide Supply Factor 2,Member 3,ATP-Binding Cassette Sub-Family B Member 3,ABC (ATP Binding Cassette),Antigen Peptide Transporter 2,Peptide Transporter TAP2,ABC Transporter,Y1 |
|
| Human |
|
| 6891 |
|
| Q03519 |
|
| QPNLPSPGTL APTTLQGVVK FQDVSFAYPN RPDRPVLKGL TFTLRPGEVT ALVGPNGSGK STVAALLQNL YQPTGGQVLL DEKPISQYEH CYLHSQVVSV GQEPVLFSGS VRNNIAYGLQ SCEDDKVMAA AQAAHADDFI QEMEHGIYTD VGEKGSQLAA GQKQRLAIAR ALVRDPRVLI LDEATSALDV QCEQALQDWN SRGDRTVLVI AHRLQTVQRA HQILVLQEGK LQKLAQL |
|
| Recombinant fusion protein containing a sequence corresponding to amino acids 450-686 of human TAP2 (NP_001276972.1). |
|
| Rabbit |
|
| Affinity Purified Monoclonal IgG |
|
| WB, ELISA |
|
| Human |
|
| 76kDa |
|
| WB,1:1000 - 1:4000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
|
|
Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
|
|
|
Shipped at ambient temperature.
|
|
|
Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
|
|
| .jpg )
Western blot analysis of various lysates using TAP2 Rabbit mAb (LTA24796) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Negative control (NC): HL-60|Exposure time: 30s. |
