|
| SMPD1 Rabbit mAb |
|
| LTA24771 |
|
| 100ul |
|
|
$750
In stock
|
|
| The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. |
|
| ASM; NPD; ASMASE |
|
| 6609,ASM,SMPD1,ASMASE,NPD,sphingomyelin phosphodiesterase 1,sphingomyelin phosphodiesterase,acid sphingomyelinase,acid lysosomal,P17405,Sphingomyelin Phosphodiesterase 1,Acid Sphingomyelinase,Acid Lysosomal,Sphingomyelin Phosphodiesterase,EC 3.1.4.12,ASMase,SMPD1/ASM |
|
| Human |
|
| 6609 |
|
| P17405 |
|
| PARLHRIVPRLRDVFGWGNLTCPICKGLFTAINLGLKKEPNVARVGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGHWDIFSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPAGPFDMVYWTGDIPAHDVWHQTRQDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNSFPPPFIEGNHSS |
|
| Recombinant fusion protein containing a sequence corresponding to amino acids 70-340 of human SMPD1 (NP_000534.3). |
|
| Rabbit |
|
| Affinity Purified Monoclonal IgG |
|
| IHC-P, ELISA |
|
| Human, Mouse, Rat |
|
| 70kDa |
|
| IHC-P,1:200 - 1:2000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
|
|
Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
|
|
|
Shipped at ambient temperature.
|
|
|
Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
|
|
| .jpg )
Immunohistochemistry analysis of paraffin-embedded Human liver tissue using SMPD1 Rabbit mAb (LTA24771) at a dilution of 1:300 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Buffer (pH 6.0) prior to IHC staining. |
