RUNX1 Rabbit mAb

Product Name
RUNX1 Rabbit mAb
Catalog Number
LTA24718
Quantity
100ul
Price
$750 In stock
Description
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Alias
AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; CBF2alpha; AML1-EVI-1; PEBP2alpha
Keywords
861,sc-8564,sc-8563,sc-28679,AML1,AML1 EVI 1,AMLCR1,CBF alpha 2,CBFA2,EVI 1,Oncogene AML 1,PEA2 alpha B,PEBP2 alpha B,PEBP2aB,RUNX1,AML1-EVI-1,CBF2alpha,EVI-1,PEBP2alpha,runt related transcription factor 1,runt-related transcription factor 1,AML1-EVI-1 fusion protein,CBF-alpha-2,PEA2-alpha B,PEBP2-alpha B,RUNX1/ZNF687 fusion,SL3-3 enhancer factor 1 alpha B subunit,SL3/AKV core-binding factor alpha B subunit,acute myeloid leukemia 1 protein,core-binding factor,runt domain,alpha subunit 2,oncogene AML-1,polyomavirus enhancer-binding protein 2 alpha B subunit,Q01196,Runx1,Runt Related Transcription Factor 1,Polyomavirus Enhancer-Binding Protein 2 Alpha B Subunit,SL3/AKV Core-Binding Factor Alpha B Subunit,SL3-3 Enhancer Factor 1 Alpha B Subunit,Runt-Related Transcription Factor 1,Acute Myeloid Leukemia 1 Protein,Oncogene AML-1,PEBP2-Alpha B,PEA2-Alpha B,Core-Binding Factor,Runt Domain,Alpha Subunit 2,Core-Binding Factor Subunit Alpha-2,AML1-EVI-1 Fusion Protein,Acute Myeloid Leukemia 1,Aml1 Oncogene,CBF-Alpha-2,RUNX1 / AML1
Gene Template Species
Human
Gene/Protein ID
861
SWISS ID
Q01196
Antigen Sequence
GTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSE
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 101-200 of human RUNX1 (NP_001001890.1).
Animal Source
Rabbit
Antibody Type
Affinity Purified Monoclonal IgG
Applications
WB, ELISA
Cross-Reactivity
Human, Mouse
Molecular Weight
49kDa
Recommended Dilution
WB,1:1000 - 1:6000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements.
Stability and Storage

Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.

Image
 RUNX1 Rabbit mAb

Western blot analysis of various lysates using RUNX1 Rabbit mAb (LTA24718) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 3s.

  • 4 Units in Stock

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