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| RIP3 Rabbit mAb |
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| LTA24826 |
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| 100ul |
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$750
In stock
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| The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. |
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| RIP3 |
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| 11035,sc-47368,sc-135171,Receptor interacting protein 3,RIP 3,RIP like protein kinase 3,RIP3,RIPK3,receptor interacting serine/threonine kinase 3,receptor-interacting serine/threonine-protein kinase 3,RIP-3,RIP-like protein kinase 3,receptor interacting protein 3,Q9Y572,Receptor Interacting Serine/Threonine Kinase 3,RIP-Like Protein Kinase 3,Receptor-Interacting Serine/Threonine-Protein Kinase 3,Receptor-Interacting Serine-Threonine Kinase 3,Receptor Interacting Protein 3,Receptor-Interacting Protein 3,EC 2.7.11.1 |
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| Human |
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| 11035 |
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| Q9Y572 |
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| MSCVKLWPSG APAPLVSIEE LENQELVGKG GFGTVFRAQH RKWGYDVAVK IVNSKAISRE VKAMASLDNE FVLRLEGVIE KVNWDQDPKP ALVTKFMENG SLSGLLQSQC PRPWPLLCRL LKEVVLGMFY LHDQNPVLLH RDLKPSNVLL DPELHVKLAD FGLSTFQGGS QSGTGSGEPG GTLGYLAPEL FVNVNRKAST ASDVYSFGIL MWAVLAGREV ELPTEPSLVY EAVCNRQNRP SLAELPQAGP ETPGLEGLKE LMQLCWSSEP KDRPSFQECL PKTDEVF |
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| Recombinant Protein corresponding to a sequence within amino acids 1-287 of human RIP3 (NP_006862.2). |
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| Rabbit |
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| Affinity Purified Monoclonal IgG |
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| IF/ICC, ELISA |
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| Mouse |
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| 57kDa |
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| IF/ICC,1:100 - 1:400|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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| .jpg )
Confocal imaging of L-929 cells using RIP3 Rabbit mAb (LTA24826, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (LT007, dilution 1:500) (Red). The cells were counterstained with _-Tubulin Mouse mAb (AC012, dilution 1:400) followed by incubation with ABflo® 488-conjugated Goat Anti-Mouse IgG (H+L) Ab (LT076, dilution 1:500) (Green). DAPI was used for nuclear staining (Blue). Objective: 100x. |
