| PER1 Rabbit mAb |
| LTA24777 |
| 100ul |
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$750
In stock
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| This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described. |
| PER; hPER; RIGUI |
| 5187,sc-7723,sc-7724,sc-25362,hPER,hPER1,KIAA0482,PER,PER1,period homolog 1 (Drosophila),RIGUI,period circadian clock 1,period circadian protein homolog 1,Period,drosophila,homolog of,circadian clock protein PERIOD 1,circadian pacemaker protein RIGUI,period homolog 1,O15534,Period Circadian Regulator 1,Circadian Clock Protein PERIOD 1,Period Circadian Clock 1,HPER1,Period Circadian Protein Homolog 1,Circadian Pacemaker Protein RIGUI,Circadian Pacemaker Protein Rigui,Drosophila,Homolog Of,Period (Drosophila) Homolog 1,Period Homolog 1 (Drosophila),Period Homolog 1,HPER |
| Human |
| 5187 |
| O15534 |
| MSGPLEGADGGGDPRPGESFCPGGVPSPGPPQHRPCPGPSLADDTDANSNGSSGNESNGHESRGASQRSSHSSSSGNGKDSALLETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPSTSGCSSEQSARARTQKELMTALRELKLRLPPERRGKGRSGTLATLQYALACVKQVQANQEYYQQWSLEEGEPCSMDMSTY |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PER1 (NP_002607.2). |
| Rabbit |
| Affinity Purified Monoclonal IgG |
| IHC-P, ELISA |
| Human, Mouse |
| 136kDa |
| IHC-P,1:200 - 1:800|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma tissue using PER1 Rabbit mAb (LTA24777) at a dilution of 1:300 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Buffer (pH 6.0) prior to IHC staining. |