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| This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. |
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| 5156,sc-31178,sc-431,sc-338,CD140A,CD140a antigen,PDGF R alpha,PDGF receptor alpha,PDGFR2,PDGFRA,PDGFR_,PDGFR-_,Rhe PDGFRA,PDGFR-2,platelet derived growth factor receptor alpha,platelet-derived growth factor receptor alpha,CD140 antigen-like family member A,PDGF-R-alpha,alpha-type platelet-derived growth factor receptor,platelet-derived growth factor receptor 2,platelet-derived growth factor receptor,alpha polypeptide,P16234,Platelet Derived Growth Factor Receptor Alpha,Platelet-Derived Growth Factor Receptor,Alpha Polypeptide,Alpha-Type Platelet-Derived Growth Factor Receptor,Platelet-Derived Growth Factor Receptor 2,CD140 Antigen-Like Family Member A,CD140a Antigen,PDGF-R-Alpha,Platelet-Derived Growth Factor Receptor Alpha,Alpha Platelet-Derived Growth Factor Receptor,Platelet-Derived Growth Factor Alpha Receptor,PDGFR-Alpha,EC 2.7.10.1,RHEPDGFRA,GAS9 |
