Neurogranin (NRGN) Rabbit mAb

Product Name
Neurogranin (NRGN) Rabbit mAb
Catalog Number
LTA24732
Quantity
100ul
Price
$750 In stock
Description
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
Alias
RC3; hng
Keywords
4900,sc-18336,sc-50401,hng,Neurogranin,Ng,NRGN,P17,RC3,neurogranin,calmodulin-binding protein,neurogranin (protein kinase C substrate,RC3),ng,protein kinase C substrate,Q92686,Neurogranin (Protein Kinase C Substrate,Calmodulin-Binding Protein,Protein Kinase C Substrate,Hng
Gene Template Species
Human
Gene/Protein ID
4900
SWISS ID
Q92686
Antigen Sequence
DCCTENACSK PDDDILDIPL DDPGANAAAA KIQASFRGHM ARKKIKSGER GRKGPGPGGP GGAGVARGGA GGGPSGD
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 2-78 of human Neurogranin (NRGN) (NP_001119653.1).
Animal Source
Rabbit
Antibody Type
Affinity Purified Monoclonal IgG
Applications
WB, ELISA
Cross-Reactivity
Mouse, Rat
Molecular Weight
8kDa
Recommended Dilution
WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements.
Stability and Storage

Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.

Image
 Neurogranin (NRGN) Rabbit mAb

Western blot analysis of various lysates using Neurogranin (NRGN) Rabbit mAb (LTA24732) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (LT00021).|Negative control (NC): Mouse lung|Exposure time: 45s.

  • 4 Units in Stock

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