| Neurogranin (NRGN) Rabbit mAb |
| LTA24732 |
| 100ul |
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$750
In stock
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| Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. |
| RC3; hng |
| 4900,sc-18336,sc-50401,hng,Neurogranin,Ng,NRGN,P17,RC3,neurogranin,calmodulin-binding protein,neurogranin (protein kinase C substrate,RC3),ng,protein kinase C substrate,Q92686,Neurogranin (Protein Kinase C Substrate,Calmodulin-Binding Protein,Protein Kinase C Substrate,Hng |
| Human |
| 4900 |
| Q92686 |
| DCCTENACSK PDDDILDIPL DDPGANAAAA KIQASFRGHM ARKKIKSGER GRKGPGPGGP GGAGVARGGA GGGPSGD |
| Recombinant fusion protein containing a sequence corresponding to amino acids 2-78 of human Neurogranin (NRGN) (NP_001119653.1). |
| Rabbit |
| Affinity Purified Monoclonal IgG |
| WB, ELISA |
| Mouse, Rat |
| 8kDa |
| WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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Western blot analysis of various lysates using Neurogranin (NRGN) Rabbit mAb (LTA24732) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (LT00021).|Negative control (NC): Mouse lung|Exposure time: 45s. |