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| LILRB1/CD85j Rabbit mAb |
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| LTA24743 |
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| 100ul |
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$750
In stock
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| This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. |
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| ILT2; LIR1; MIR7; PIRB; CD85J; ILT-2; LIR-1; MIR-7; PIR-B |
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| 10859,LILRB1,CD85J,ILT-2,ILT2,LIR-1,LIR1,MIR-7,MIR7,PIR-B,PIRB,leukocyte immunoglobulin like receptor B1,leukocyte immunoglobulin-like receptor subfamily B member 1,CD85 antigen-like family member J,Ig-like transcript 2,leucocyte Ig-like receptor B1,leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform,leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains),member 1,monocyte/macrophage immunoglobulin-like receptor 7,myeloid inhibitory receptor 7,Q8NHL6,Leukocyte Immunoglobulin Like Receptor B1,Leukocyte Immunoglobulin-Like Receptor,Subfamily B (With TM And ITIM Domains),Member 1,Monocyte/Macrophage Immunoglobulin-Like Receptor 7,CD85 Antigen-Like Family Member J,Leucocyte Ig-Like Receptor B1,Myeloid Inhibitory Receptor 7,Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 Soluble Isoform,Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1,Leukocyte Immunoglobulin-Like Receptor 1,Immunoglobulin-Like Transcript 2,Ig-Like Transcript 2,CD85j Antigen |
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| Human |
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| 10859 |
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| Q8NHL6 |
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| GHLPKPTLWA EPGSVITQGS PVTLRCQGGQ ETQEYRLYRE KKTAPWITRI PQELVKKGQF PIPSITWEHT GRYRCYYGSD TAGRSESSDP LELVVTGAYI KPTLSAQPSP VVNSGGNVTL QCDSQVAFDG FILCKEGEDE HPQCLNSQPH ARGSSRAIFS VGPVSPSRRW WYRCYAYDSN SPYEWSLPSD LLELLVLGVS KKPSLSVQPG PIVAPEETLT LQCGSDAGYN RFVLYKDGER DFLQLAGAQP QAGLSQANFT LGPVSRSYGG QYRCYGAHNL SSEWSAPSDP LDILIAGQFY DRVSLSVQPG PTVASGENVT LLCQSQGWMQ TFLLTKEGAA DDPWRLRSTY QSQKYQAEFP MGPVTSAHAG TYRCYGSQSS KPYLLTHPSD PLELVVSGPS GGPSSPTTGP TSTSGPEDQP LTPTGSDPQS GLGRH |
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| Recombinant fusion protein containing a sequence corresponding to amino acids 24-458 of human LILRB1/CD85j (NP_006660.4). |
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| Rabbit |
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| Affinity Purified Monoclonal IgG |
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| WB, ELISA |
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| Human |
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| 71kDa |
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| WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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| .jpg )
Western blot analysis of various lysates using LILRB1/CD85j Rabbit mAb (LTA24743) at 1:2000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (LT00021).|Negative control (NC): K-562|Exposure time: 60s. |
