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| [KD Validated] DCK Rabbit mAb |
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| LTA24807 |
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| 100ul |
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$750
In stock
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| Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. |
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| DCK |
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| 1633,sc-49283,sc-49284,sc-49285,sc-99008,DCK,deoxycytidine kinase,deoxynucleoside kinase,P27707,Dck,Deoxycytidine Kinase,Deoxynucleoside Kinase,EC 2.7.1.74 |
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| Human |
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| 1633 |
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| P27707 |
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| MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL |
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| Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1). |
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| Rabbit |
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| Affinity Purified Monoclonal IgG |
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| WB, ELISA |
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| Human, Rat |
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| 31kDa |
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| WB,1:2000 - 1:4000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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| ![[KD Validated] DCK Rabbit mAb]( /peptide-product/images/antibody-products/LTA24807/LTA24807_WB_02_(1166874).jpg )
Western blot analysis of lysates from wild type (WT) and DCK knockdown (KD) 293F cells using [KD Validated] DCK Rabbit mAb (LTA24807) at 1:2000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 60s. |
