| [KD Validated] beta 2 Microglobulin Rabbit mAb |
| LTA24759 |
| 100ul |
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$750
In stock
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| This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. |
| IMD43 |
| 567,sc-8360,sc-8362,sc-27039,sc-15366,B2M,Beta-2-microglobulin,HDCMA22P,IMD43,beta-2-microglobulin,beta chain of MHC class I molecules,beta-2-microglobin,P61769,Beta-2-Microglobulin,Beta Chain Of MHC Class I Molecules,Beta-2-Microglobin,beta 2 Microglobulin |
| Human |
| 567 |
| P61769 |
| IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM |
| Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human beta 2 Microglobulin (NP_004039.1). |
| Rabbit |
| Affinity Purified Monoclonal IgG |
| WB, ELISA |
| Human |
| 14kDa |
| WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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Western blot analysis of lysates from wild type (WT) and _2-microglobulin knockdown (KD) HeLa cells using [KD Validated] beta 2 Microglobulin Rabbit mAb (LTA24759) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 60s. |