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| GCSH Rabbit mAb |
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| LTA24790 |
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| 100ul |
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$750
In stock
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| Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome. |
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| GCE; NKH |
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| 2653,GCE,GCSH,NKH,glycine cleavage system protein H,glycine cleavage system H protein,mitochondrial,glycine cleavage system protein H (aminomethyl carrier),lipoic acid-containing protein,mitochondrial glycine cleavage system H-protein,P23434,Glycine Cleavage System Protein H,Lipoic Acid-Containing Protein,Glycine Cleavage System Protein H (Aminomethyl Carrier),Glycine Cleavage System H Protein,Mitochondrial,Mitochondrial Glycine Cleavage System H-Protein |
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| Human |
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| 2653 |
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| P23434 |
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| SVRKFTEKHE WVTTENGIGT VGISNFAQEA LGDVVYCSLP EVGTKLNKQD EFGALESVKA ASELYSPLSG EVTEINEALA ENPGLVNKSC YEDGWLIKMT LSNPSELDEL MSEEAYEKYI KSIEE |
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| Recombinant fusion protein containing a sequence corresponding to amino acids 49-173 of human GCSH (NP_004474.2). |
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| Rabbit |
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| Affinity Purified Monoclonal IgG |
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| IF/ICC, ELISA |
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| Human |
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| 19kDa |
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| IF/ICC,1:100 - 1:400|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
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Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
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Shipped at ambient temperature.
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Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
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| .jpg )
Confocal imaging of U-2 OS cells using GCSH Rabbit mAb (LTA24790, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (LT007, dilution 1:500) (Red). The cells were counterstained with _-Tubulin Mouse mAb (AC012, dilution 1:400) followed by incubation with ABflo® 488-conjugated Goat Anti-Mouse IgG (H+L) Ab (LT076, dilution 1:500) (Green). DAPI was used for nuclear staining (Blue). Objective: 100x. |
