{"id":736,"date":"2021-07-12T14:52:13","date_gmt":"2021-07-12T18:52:13","guid":{"rendered":"https:\/\/www.lifetein.com\/blog\/?p=736"},"modified":"2024-11-16T21:30:44","modified_gmt":"2024-11-17T02:30:44","slug":"lifetein-made-rabbit-polyclonal-anti-gm-and-anti-gn-antibodies","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/lifetein-made-rabbit-polyclonal-anti-gm-and-anti-gn-antibodies\/","title":{"rendered":"Rabbit Polyclonal Anti-gM and Anti-gN Antibodies Using Synthetic Long Peptides"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Human cytomegalovirus (HCMV) is currently a major cause of congenital disease in newborns and organ failure in transplant recipients. Various vaccine strategies have been developed, including live attenuated, recombinant viral proteins, dense bodies, vector vaccine subunit, or synthetic peptide epitopes. The rabbit polyclonal anti-gM and anti-gN antibodies were elicited by vaccinating animals with synthesized peptide sequences of gM (1-13aa and 345-372aa) and gN (61-101aa). Animal immunization and sera collection were performed at Lifetein, LLC (Hillsborough, NJ, USA). The sera were affinity-purified by its corresponding peptides.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">These formulations have been extensively tested using different animal models and have shown promising immunogenicity and protective efficacy. Some of these strategies have already progressed to clinical trials with humans. The study was studied by Vaccine Analytical Research Development and Vaccine Process Development Merck &amp; Co., Inc., Kenilworth, NJ, USA.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"668\" height=\"495\" src=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2021\/07\/Fig-2-Virtual-three-dimensional-model-of-human-cytomegalovirus-showing-various.png\" alt=\"Synthetic Long Peptides\" class=\"wp-image-737\" srcset=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2021\/07\/Fig-2-Virtual-three-dimensional-model-of-human-cytomegalovirus-showing-various.png 668w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2021\/07\/Fig-2-Virtual-three-dimensional-model-of-human-cytomegalovirus-showing-various-300x222.png 300w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2021\/07\/Fig-2-Virtual-three-dimensional-model-of-human-cytomegalovirus-showing-various-405x300.png 405w\" sizes=\"(max-width: 668px) 100vw, 668px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Human cytomegalovirus (HCMV) is currently a major cause of congenital disease in newborns and organ failure in transplant recipients. Various vaccine strategies have been developed, including live attenuated, recombinant viral proteins, dense bodies, vector vaccine subunit, or synthetic peptide epitopes. &hellip; <a href=\"https:\/\/www.lifetein.com\/blog\/lifetein-made-rabbit-polyclonal-anti-gm-and-anti-gn-antibodies\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":737,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-736","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"LifeTein Made Custom Rabbit Polyclonal Anti-gM and Anti-gN Antibodies for Human Cytomegalovirus. The long peptides were synthesized by LifeTein.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"LifeTein Peptide\"\/>\n\t<meta name=\"google-site-verification\" content=\"xKDW6DUiGuZ6nwglNeWlVWTgzTtMPzas13ROL63ytTc\" \/>\n\t<meta name=\"msvalidate.01\" content=\"5B15601215D876311F84CFEFB0F72F18\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.lifetein.com\/blog\/lifetein-made-rabbit-polyclonal-anti-gm-and-anti-gn-antibodies\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.10\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"LifeTein Peptide Synthesis Blog\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Rabbit Polyclonal Anti-gM and Anti-gN Antibodies Using Synthetic Long Peptides |\" \/>\n\t\t<meta property=\"og:description\" content=\"LifeTein Made Custom Rabbit Polyclonal Anti-gM and Anti-gN Antibodies for Human Cytomegalovirus. 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Various vaccine strategies have been developed, including live attenuated, recombinant viral proteins, dense bodies, vector vaccine subunit, or synthetic peptide epitopes. The rabbit polyclonal anti-gM and anti-gN antibodies were elicited by vaccinating animals with synthesized peptide\" \/>\n\t\t<meta name=\"twitter:creator\" content=\"@lifetein\" \/>\n\t\t<meta name=\"twitter:image\" content=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg\" \/>\n\t\t<!-- All in One SEO -->\n\n","aioseo_head_json":{"title":"Rabbit Polyclonal Anti-gM and Anti-gN Antibodies Using Synthetic Long Peptides |","description":"LifeTein Made Custom Rabbit Polyclonal Anti-gM and Anti-gN Antibodies for Human Cytomegalovirus. 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Various vaccine strategies have been developed, including live attenuated, recombinant viral proteins, dense bodies, vector vaccine subunit, or synthetic peptide epitopes. The rabbit polyclonal anti-gM and anti-gN antibodies were elicited by vaccinating animals with synthesized peptide","twitter:creator":"@lifetein","twitter:image":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg"},"aioseo_meta_data":{"post_id":"736","title":"#post_title |","description":"LifeTein Made Custom Rabbit Polyclonal Anti-gM and Anti-gN Antibodies for Human Cytomegalovirus. The long peptides were synthesized by LifeTein.","keywords":null,"keyphrases":{"focus":{"keyphrase":"Rabbit Polyclonal","score":90,"analysis":{"keyphraseInTitle":{"score":9,"maxScore":9,"error":0},"keyphraseInDescription":{"score":9,"maxScore":9,"error":0},"keyphraseLength":{"score":9,"maxScore":9,"error":0,"length":2},"keyphraseInURL":{"score":5,"maxScore":5,"error":0},"keyphraseInIntroduction":{"score":9,"maxScore":9,"error":0},"keyphraseInSubHeadings":[],"keyphraseInImageAlt":{"score":3,"maxScore":9,"error":1},"keywordDensity":{"type":"best","score":9,"maxScore":9,"error":0}}},"additional":[{"keyphrase":"synthetic peptides","score":53,"analysis":{"keyphraseInDescription":{"score":3,"maxScore":9,"error":1},"keyphraseLength":{"score":9,"maxScore":9,"error":0,"length":2},"keyphraseInIntroduction":{"score":3,"maxScore":9,"error":1},"keyphraseInImageAlt":{"score":9,"maxScore":9,"error":0},"keywordDensity":{"score":0,"type":"low","maxScore":9,"error":1}}},{"keyphrase":"Rabbit 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18:44:23","updated":"2025-06-18 02:57:23"},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.lifetein.com\/blog\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.lifetein.com\/blog\/category\/peptide_synthesis\/\" title=\"Peptide\">Peptide<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tRabbit Polyclonal Anti-gM and Anti-gN Antibodies Using Synthetic Long Peptides\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/www.lifetein.com\/blog"},{"label":"Peptide","link":"https:\/\/www.lifetein.com\/blog\/category\/peptide_synthesis\/"},{"label":"Rabbit Polyclonal Anti-gM and Anti-gN Antibodies Using Synthetic Long 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