{"id":671,"date":"2020-04-15T16:15:28","date_gmt":"2020-04-15T20:15:28","guid":{"rendered":"https:\/\/www.lifetein.com\/blog\/?p=671"},"modified":"2024-11-16T21:33:33","modified_gmt":"2024-11-17T02:33:33","slug":"peptide-library-sars-cov-2-receptor-binding-domains","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/peptide-library-sars-cov-2-receptor-binding-domains\/","title":{"rendered":"Peptide Library: SARS-CoV-2 Receptor Binding Domains"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"360\" height=\"306\" src=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/04\/Coronavirus-Antibody.png\" alt=\"\" class=\"wp-image-672\" srcset=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/04\/Coronavirus-Antibody.png 360w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/04\/Coronavirus-Antibody-300x255.png 300w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/04\/Coronavirus-Antibody-353x300.png 353w\" sizes=\"(max-width: 360px) 100vw, 360px\" \/><figcaption>Coronavirus<\/figcaption><\/figure><\/div>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"700\" height=\"395\" src=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/04\/Receptor-Binding-Domain-COVID-Spike-S1-Protein-2.png\" alt=\"\" class=\"wp-image-673\" srcset=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/04\/Receptor-Binding-Domain-COVID-Spike-S1-Protein-2.png 700w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/04\/Receptor-Binding-Domain-COVID-Spike-S1-Protein-2-300x169.png 300w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/04\/Receptor-Binding-Domain-COVID-Spike-S1-Protein-2-500x282.png 500w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><figcaption>Coronavirus receptor binding domain. The key receptor binding domain (residues 319-541) is highlighted in yellow. Variable amino acid residues between SARS-CoV-2 and SARS-CoV are highlighted in cyan. Tyr 489, Asn 487, Gln 493, Tyr 505 are important for ACE2 binding.<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">LifeTein can help in your research with custom peptide synthesis of the following specific proteins: SARS-CoV-2 Receptor Binding Domains, SARS-CoV-2 Nucleocapsid Fragments, T-cell and B-cell Epitopes of SARS-CoV-2, Fusion Inhibitors Targeting HR1 Domain of the SARS-CoV-2 Spike Proteins, Inhibitors of SARS-CoV-2 Mpro\/3CLpro\/C30 Endopeptidase, ACE2 Inhibitors and Substrates, and AT2 Receptor Agonists and Antagonists.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pool of 22 peptides derived from a peptide design (15mers with 5 aa overlap) through the receptor binding domain of S1 protein.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Modifications<\/strong>: N-Terminal: Biotin Labeling<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Amount<\/strong>: 1mg per peptide<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Purity<\/strong>: 95%<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Delivery Format<\/strong>: Freeze dried powder<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Application(s)<\/strong>: Antibody screening, T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, Cellular immune response<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Indication(s)\/Topic(s)<\/strong>: Covid-19, Infection, Respiratory infection<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Delivery Time<\/strong>: 2 weeks<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>SARS-CoV-2 Receptor Binding Domains Overlapping Peptide Pools<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>QPTESIVRFPNITNL<\/li><li>NITNLCPFGEVFNAT<\/li><li>VFNATRFASVYAWNR<\/li><li>YAWNRKRISNCVADY<\/li><li>CVADYSVLYNSASFS<\/li><li>SASFSTFKCYGVSPT<\/li><li>GVSPTKLNDLCFTNV<\/li><li>CFTNVYADSFVIRGD<\/li><li>VIRGDEVRQIAPGQT<\/li><li>APGQTGKIADYNYKL<\/li><li>YNYKLPDDFTGCVIA<\/li><li>GCVIAWNSNNLDSKV<\/li><li>LDSKVGGNYNYLYRL<\/li><li>YLYRLFRKSNLKPFE<\/li><li>LKPFERDISTEIYQA<\/li><li>EIYQAGSTPCNGVEG<\/li><li>NGVEGFNCYFPLQSY<\/li><li>PLQSYGFQPTNGVGY<\/li><li>NGVGYQPYRVVVLSF<\/li><li>VVLSFELLHAPATVC<\/li><li>PATVCGPKKSTNLVK<\/li><li>TNLVKNKCVNFNFNG<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>LifeTein can help in your research with custom peptide synthesis of the following specific proteins: SARS-CoV-2 Receptor Binding Domains, SARS-CoV-2 Nucleocapsid Fragments, T-cell and B-cell Epitopes of SARS-CoV-2, Fusion Inhibitors Targeting HR1 Domain of the SARS-CoV-2 Spike Proteins, Inhibitors of &hellip; <a href=\"https:\/\/www.lifetein.com\/blog\/peptide-library-sars-cov-2-receptor-binding-domains\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":673,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-671","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/comments?post=671"}],"version-history":[{"count":0,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/671\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media\/673"}],"wp:attachment":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media?parent=671"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/categories?post=671"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/tags?post=671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}