{"id":426,"date":"2018-02-15T15:56:07","date_gmt":"2018-02-15T20:56:07","guid":{"rendered":"https:\/\/www.lifetein.com\/blog\/?p=426"},"modified":"2024-11-16T22:18:45","modified_gmt":"2024-11-17T03:18:45","slug":"noble-metal-gold-and-silver-nanoparticle-are-conjugated-with-peptides-for-cellular-imaging","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/noble-metal-gold-and-silver-nanoparticle-are-conjugated-with-peptides-for-cellular-imaging\/","title":{"rendered":"Noble metal gold and silver nanoparticle are conjugated with peptides for cellular imaging"},"content":{"rendered":"<p>Noble metal gold (Au) and silver (Ag) nanoparticles (NPs) are used to conjugate with M3 peptides. The AuNPs-sGFP and AuNPs-M3 peptide forms an active SERS hot spot through self-assembly and GFP complementation. The nanoparticles self-assemble into surface-enhanced Raman-scattering (SERS) nanoclusters. The nanocluster can be a contrast agent for multimodal SERS and photoacoustic microscopy with single-cell sensitivity.<\/p>\n<div id=\"attachment_427\" style=\"width: 310px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" aria-describedby=\"caption-attachment-427\" class=\"size-medium wp-image-427\" src=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/02\/AuNPs-coated-with-M3-peptides-GFP-300x142.png\" alt=\"AuNPs coated with M3 peptides-GFP\" width=\"300\" height=\"142\" srcset=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/02\/AuNPs-coated-with-M3-peptides-GFP-300x142.png 300w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/02\/AuNPs-coated-with-M3-peptides-GFP-768x365.png 768w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/02\/AuNPs-coated-with-M3-peptides-GFP-1024x486.png 1024w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/02\/AuNPs-coated-with-M3-peptides-GFP-500x237.png 500w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/02\/AuNPs-coated-with-M3-peptides-GFP.png 1866w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><p id=\"caption-attachment-427\" class=\"wp-caption-text\">AuNPs coated with M3 peptides-GFP<\/p><\/div>\n<p>Reference: M3 peptide was purchased from LifeTein.<\/p>\n<h2 class=\"tighten-line-height small-space-below\" data-test=\"article-title\">Cellular imaging by targeted assembly of hot-spot SERS and photoacoustic nanoprobes using split-fluorescent protein scaffolds<\/h2>\n<p>https:\/\/www.nature.com\/articles\/s41467-018-03046-w<\/p>\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Noble metal gold (Au) and silver (Ag) nanoparticles (NPs) are used to conjugate with M3 peptides. The AuNPs-sGFP and AuNPs-M3 peptide forms an active SERS hot spot through self-assembly and GFP complementation. The nanoparticles self-assemble into surface-enhanced Raman-scattering (SERS) nanoclusters. &hellip; <a href=\"https:\/\/www.lifetein.com\/blog\/noble-metal-gold-and-silver-nanoparticle-are-conjugated-with-peptides-for-cellular-imaging\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1383,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[83,85,84],"class_list":["post-426","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis","tag-gfp","tag-hot-spot","tag-m3-peptide"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Noble metal gold (Au) and silver (Ag) nanoparticle (NPs) are used to conjugate with M3 peptides. The AuNPs-sGFP andAuNPs-M3 peptide form SERS active hot spot through self-assembly and GFP complementation. The nanoparticles self-assemble into surface-enhanced Raman-scattering (SERS) nanoclusters. The nanocluster can be used as contrast agents for multimodal SERS and photoacoustic microscopy with single-cell sensitivity.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"LifeTein Peptide\"\/>\n\t<meta name=\"google-site-verification\" content=\"xKDW6DUiGuZ6nwglNeWlVWTgzTtMPzas13ROL63ytTc\" \/>\n\t<meta name=\"msvalidate.01\" content=\"5B15601215D876311F84CFEFB0F72F18\" \/>\n\t<meta name=\"keywords\" content=\"gfp,peptide,nanoparticles,self-assemble,hot spot,m3 peptide\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.lifetein.com\/blog\/noble-metal-gold-and-silver-nanoparticle-are-conjugated-with-peptides-for-cellular-imaging\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.8\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"LifeTein Peptide Synthesis Blog\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Noble metal gold and silver nanoparticle are conjugated with peptides for cellular imaging | LifeTein Peptide Blog\" \/>\n\t\t<meta property=\"og:description\" content=\"Noble metal gold (Au) and silver (Ag) nanoparticle (NPs) are used to conjugate with M3 peptides. The AuNPs-sGFP andAuNPs-M3 peptide form SERS active hot spot through self-assembly and GFP complementation. The nanoparticles self-assemble into surface-enhanced Raman-scattering (SERS) nanoclusters. The nanocluster can be used as contrast agents for multimodal SERS and photoacoustic microscopy with single-cell sensitivity.\" \/>\n\t\t<meta property=\"og:url\" content=\"https:\/\/www.lifetein.com\/blog\/noble-metal-gold-and-silver-nanoparticle-are-conjugated-with-peptides-for-cellular-imaging\/\" \/>\n\t\t<meta property=\"fb:admins\" content=\"233983946638783\" \/>\n\t\t<meta property=\"og:image\" content=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg\" \/>\n\t\t<meta property=\"og:image:secure_url\" content=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg\" \/>\n\t\t<meta property=\"article:tag\" content=\"gfp\" \/>\n\t\t<meta property=\"article:tag\" content=\"peptide\" \/>\n\t\t<meta property=\"article:tag\" content=\"nanoparticles\" \/>\n\t\t<meta property=\"article:tag\" content=\"self-assemble\" \/>\n\t\t<meta property=\"article:tag\" content=\"hot spot\" \/>\n\t\t<meta property=\"article:tag\" content=\"m3 peptide\" \/>\n\t\t<meta property=\"article:published_time\" content=\"2018-02-15T20:56:07+00:00\" \/>\n\t\t<meta property=\"article:modified_time\" content=\"2024-11-17T03:18:45+00:00\" \/>\n\t\t<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/LifeTein-LLC-233983946638783\/\" \/>\n\t\t<meta name=\"twitter:card\" content=\"summary\" \/>\n\t\t<meta name=\"twitter:site\" content=\"@lifetein\" \/>\n\t\t<meta name=\"twitter:title\" content=\"Noble metal gold and silver nanoparticle are conjugated with peptides for cellular imaging | LifeTein Peptide Blog\" \/>\n\t\t<meta name=\"twitter:description\" content=\"Noble metal gold (Au) and silver (Ag) nanoparticle (NPs) are used to conjugate with M3 peptides. The AuNPs-sGFP andAuNPs-M3 peptide form SERS active hot spot through self-assembly and GFP complementation. The nanoparticles self-assemble into surface-enhanced Raman-scattering (SERS) nanoclusters. The nanocluster can be used as contrast agents for multimodal SERS and photoacoustic microscopy with single-cell sensitivity.\" \/>\n\t\t<meta name=\"twitter:creator\" content=\"@lifetein\" \/>\n\t\t<meta name=\"twitter:image\" content=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg\" \/>\n\t\t<!-- All in One SEO -->\n\n","aioseo_head_json":{"title":"Noble metal gold and silver nanoparticle are conjugated with peptides for cellular imaging | LifeTein Peptide Blog","description":"Noble metal gold (Au) and silver (Ag) nanoparticle (NPs) are used to conjugate with M3 peptides. The AuNPs-sGFP andAuNPs-M3 peptide form SERS active hot spot through self-assembly and GFP complementation. The nanoparticles self-assemble into surface-enhanced Raman-scattering (SERS) nanoclusters. The nanocluster can be used as contrast agents for multimodal SERS and photoacoustic microscopy with single-cell sensitivity.","canonical_url":"https:\/\/www.lifetein.com\/blog\/noble-metal-gold-and-silver-nanoparticle-are-conjugated-with-peptides-for-cellular-imaging\/","robots":"max-image-preview:large","keywords":"gfp,peptide,nanoparticles,self-assemble,hot spot,m3 peptide","webmasterTools":{"google-site-verification":"xKDW6DUiGuZ6nwglNeWlVWTgzTtMPzas13ROL63ytTc","msvalidate.01":"5B15601215D876311F84CFEFB0F72F18","miscellaneous":""},"schema":null,"og:locale":"en_US","og:site_name":"LifeTein Peptide Synthesis Blog","og:type":"article","og:title":"Noble metal gold and silver nanoparticle are conjugated with peptides for cellular imaging | LifeTein Peptide Blog","og:description":"Noble metal gold (Au) and silver (Ag) nanoparticle (NPs) are used to conjugate with M3 peptides. The AuNPs-sGFP andAuNPs-M3 peptide form SERS active hot spot through self-assembly and GFP complementation. The nanoparticles self-assemble into surface-enhanced Raman-scattering (SERS) nanoclusters. The nanocluster can be used as contrast agents for multimodal SERS and photoacoustic microscopy with single-cell sensitivity.","og:url":"https:\/\/www.lifetein.com\/blog\/noble-metal-gold-and-silver-nanoparticle-are-conjugated-with-peptides-for-cellular-imaging\/","fb:admins":"233983946638783","og:image":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg","og:image:secure_url":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg","article:tag":["gfp","peptide","nanoparticles","self-assemble","hot spot","m3 peptide"],"article:published_time":"2018-02-15T20:56:07+00:00","article:modified_time":"2024-11-17T03:18:45+00:00","article:publisher":"https:\/\/www.facebook.com\/LifeTein-LLC-233983946638783\/","twitter:card":"summary","twitter:site":"@lifetein","twitter:title":"Noble metal gold and silver nanoparticle are conjugated with peptides for cellular imaging | LifeTein Peptide Blog","twitter:description":"Noble metal gold (Au) and silver (Ag) nanoparticle (NPs) are used to conjugate with M3 peptides. 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