{"id":373,"date":"2018-01-30T16:01:57","date_gmt":"2018-01-30T21:01:57","guid":{"rendered":"https:\/\/www.lifetein.com\/blog\/?p=373"},"modified":"2024-11-16T22:24:47","modified_gmt":"2024-11-17T03:24:47","slug":"monitoring-t-cell-dendritic-cell-interactions-in-vivo-using-labeled-peptides","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/monitoring-t-cell-dendritic-cell-interactions-in-vivo-using-labeled-peptides\/","title":{"rendered":"Monitoring T cell\u2013dendritic cell interactions in vivo using labeled peptides"},"content":{"rendered":"<p>The SrtA substrates Biotin\u2013aminohexanoic acid\u2013LPETGS and SELPETGG were used to interact with immune cells \u2018Labelling Immune Partnerships by SorTagging Intercellular Contacts\u2019 (LIPSTIC). The peptide-receptor interactions enable the direct measurement of dynamic cell-cell interactions. The peptides are flexible tools with different receptor-ligand pairs and a range of detectable labels.<\/p>\n<div id=\"attachment_374\" style=\"width: 310px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" aria-describedby=\"caption-attachment-374\" class=\"size-medium wp-image-374\" src=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Picture1-300x103.png\" alt=\"peptide-receptor interaction\" width=\"300\" height=\"103\" srcset=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Picture1-300x103.png 300w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Picture1.png 424w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><p id=\"caption-attachment-374\" class=\"wp-caption-text\">Schematic representation of the LIPSTIC approach<\/p><\/div>\n<h2>\u00a0<\/h2>\n<h2 style=\"text-align: center;\"><a href=\"https:\/\/www.nature.com\/articles\/nature25442\" target=\"_blank\" rel=\"nofollow noopener\"><strong>Nature<\/strong>, Monitoring T cell\u2013dendritic cell interactions in vivo by intercellular enzymatic labeling<\/a><\/h2>\n<p>Peptide Biotin\u2013aminohexanoic acid\u2013LPETGS, SELPETGG was purchased from LifeTein.<\/p>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The SrtA substrates Biotin\u2013aminohexanoic acid\u2013LPETGS and SELPETGG were used to interact with immune cells \u2018Labelling Immune Partnerships by SorTagging Intercellular Contacts\u2019 (LIPSTIC). The peptide-receptor interactions enable the direct measurement of dynamic cell-cell interactions. The peptides are flexible tools with different &hellip; <a href=\"https:\/\/www.lifetein.com\/blog\/monitoring-t-cell-dendritic-cell-interactions-in-vivo-using-labeled-peptides\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":2132,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[3,67,66],"class_list":["post-373","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis","tag-cell-penetrating-peptide-synthesis","tag-peptide-receptor","tag-receptor-ligand"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/373","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/comments?post=373"}],"version-history":[{"count":0,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/373\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media\/2132"}],"wp:attachment":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media?parent=373"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/categories?post=373"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/tags?post=373"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}