{"id":290,"date":"2016-01-14T10:41:38","date_gmt":"2016-01-14T15:41:38","guid":{"rendered":"http:\/\/www.lifetein.com\/blog\/?p=290"},"modified":"2024-11-16T22:35:16","modified_gmt":"2024-11-17T03:35:16","slug":"nanoparticles-get-help-from-cell-penetrating-peptides","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/nanoparticles-get-help-from-cell-penetrating-peptides\/","title":{"rendered":"Nanoparticles Get Help from Cell-Permeable Peptides"},"content":{"rendered":"<p>Some cell-permeable peptides can carry cargo across the cell membrane even without any covalent links. Biotinylated peptides, including L\u2014and D-TAT peptides made by LifeTein, were used in this study to show that two types of cell surface receptors, heparan sulfate proteoglycans, and Neuropilin-1, play critical roles in the delivery of silver-based nanoparticles into cells by cell-permeable peptides.<\/p>\n<h2 style=\"text-align: center;\">Nano Particles &amp; Cell-Permeable Peptides<\/h2>\n<p><strong>Science Advances\u00a0<\/strong>06 Nov 2015: Vol. 1, no. 10, e1500821 DOI: 10.1126\/sciadv.1500821.\u00a0 <a href=\"http:\/\/advances.sciencemag.org\/content\/1\/10\/e1500821.full\">Neuropilin-1 and heparan sulfate proteoglycans cooperate in cellular uptake of nanoparticles functionalized by cationic CPP peptides.<\/a><\/p>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some cell-permeable peptides can carry cargo across the cell membrane even without any covalent links. Biotinylated peptides, including L\u2014and D-TAT peptides made by LifeTein, were used in this study to show that two types of cell surface receptors, heparan sulfate &hellip; <a href=\"https:\/\/www.lifetein.com\/blog\/nanoparticles-get-help-from-cell-penetrating-peptides\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1886,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[4],"tags":[60,3],"class_list":["post-290","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis","tag-biotinylation","tag-cell-penetrating-peptide-synthesis"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"Biotinylated peptides, including L- and D-TAT peptides made by LifeTein were used 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22:27:49","updated":"2025-06-18 02:43:16"},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.lifetein.com\/blog\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.lifetein.com\/blog\/category\/peptide_synthesis\/\" title=\"Peptide\">Peptide<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tNanoparticles Get Help from Cell-Permeable Peptides\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/www.lifetein.com\/blog"},{"label":"Peptide","link":"https:\/\/www.lifetein.com\/blog\/category\/peptide_synthesis\/"},{"label":"Nanoparticles Get Help from Cell-Permeable 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