{"id":290,"date":"2016-01-14T10:41:38","date_gmt":"2016-01-14T15:41:38","guid":{"rendered":"http:\/\/www.lifetein.com\/blog\/?p=290"},"modified":"2024-11-16T22:35:16","modified_gmt":"2024-11-17T03:35:16","slug":"nanoparticles-get-help-from-cell-penetrating-peptides","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/nanoparticles-get-help-from-cell-penetrating-peptides\/","title":{"rendered":"Nanoparticles Get Help from Cell-Permeable Peptides"},"content":{"rendered":"<p>Some cell-permeable peptides can carry cargo across the cell membrane even without any covalent links. Biotinylated peptides, including L\u2014and D-TAT peptides made by LifeTein, were used in this study to show that two types of cell surface receptors, heparan sulfate proteoglycans, and Neuropilin-1, play critical roles in the delivery of silver-based nanoparticles into cells by cell-permeable peptides.<\/p>\n<h2 style=\"text-align: center;\">Nano Particles &amp; Cell-Permeable Peptides<\/h2>\n<p><strong>Science Advances\u00a0<\/strong>06 Nov 2015: Vol. 1, no. 10, e1500821 DOI: 10.1126\/sciadv.1500821.\u00a0 <a href=\"http:\/\/advances.sciencemag.org\/content\/1\/10\/e1500821.full\">Neuropilin-1 and heparan sulfate proteoglycans cooperate in cellular uptake of nanoparticles functionalized by cationic CPP peptides.<\/a><\/p>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some cell-permeable peptides can carry cargo across the cell membrane even without any covalent links. Biotinylated peptides, including L\u2014and D-TAT peptides made by LifeTein, were used in this study to show that two types of cell surface receptors, heparan sulfate &hellip; <a href=\"https:\/\/www.lifetein.com\/blog\/nanoparticles-get-help-from-cell-penetrating-peptides\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1886,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[60,3],"class_list":["post-290","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis","tag-biotinylation","tag-cell-penetrating-peptide-synthesis"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/290","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/comments?post=290"}],"version-history":[{"count":0,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/290\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media\/1886"}],"wp:attachment":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media?parent=290"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/categories?post=290"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/tags?post=290"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}