{"id":288,"date":"2016-01-14T10:41:16","date_gmt":"2016-01-14T15:41:16","guid":{"rendered":"http:\/\/www.lifetein.com\/blog\/?p=288"},"modified":"2024-11-16T22:36:03","modified_gmt":"2024-11-17T03:36:03","slug":"predicting-type-1-diabetes-in-children","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/predicting-type-1-diabetes-in-children\/","title":{"rendered":"Predicting type 1 diabetes in children"},"content":{"rendered":"<p>MAP is a pathogenic bacterium infecting livestock and is prevalent in dairy products.\u00a0 Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after being exposed to MAP in dairy foods and generate antibodies against MAP and might subsequently develop type I diabetes.\u00a0 The hypothesis was tested using ZnT8, PI, and MAP peptides synthesized by LifeTein to assess the cross-reactivity of antibodies in sera samples from at-risk children.<\/p>\n<h2 style=\"text-align: center;\">Type 1 Diabetes in Children<\/h2>\n<p><strong>Journal of Diabetes Research<\/strong>, Article ID 5842701, in press. <a href=\"http:\/\/www.hindawi.com\/journals\/jdr\/aa\/5842701\/\">Recognition of ZnT8, Proinsulin, and Homologous MAP Peptides in Sardinian Children at Risk of T1D Precedes Detection of Classical Islet Antibodies.<\/a><\/p>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>MAP is a pathogenic bacterium infecting livestock and is prevalent in dairy products.\u00a0 Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after &hellip; <a href=\"https:\/\/www.lifetein.com\/blog\/predicting-type-1-diabetes-in-children\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1919,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[62,27],"class_list":["post-288","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis","tag-diabetes","tag-peptide"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/288","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/comments?post=288"}],"version-history":[{"count":0,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/288\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media\/1919"}],"wp:attachment":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media?parent=288"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/categories?post=288"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/tags?post=288"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}