{"id":288,"date":"2016-01-14T10:41:16","date_gmt":"2016-01-14T15:41:16","guid":{"rendered":"http:\/\/www.lifetein.com\/blog\/?p=288"},"modified":"2024-11-16T22:36:03","modified_gmt":"2024-11-17T03:36:03","slug":"predicting-type-1-diabetes-in-children","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/predicting-type-1-diabetes-in-children\/","title":{"rendered":"Predicting type 1 diabetes in children"},"content":{"rendered":"<p>MAP is a pathogenic bacterium infecting livestock and is prevalent in dairy products.\u00a0 Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after being exposed to MAP in dairy foods and generate antibodies against MAP and might subsequently develop type I diabetes.\u00a0 The hypothesis was tested using ZnT8, PI, and MAP peptides synthesized by LifeTein to assess the cross-reactivity of antibodies in sera samples from at-risk children.<\/p>\n<h2 style=\"text-align: center;\">Type 1 Diabetes in Children<\/h2>\n<p><strong>Journal of Diabetes Research<\/strong>, Article ID 5842701, in press. <a href=\"http:\/\/www.hindawi.com\/journals\/jdr\/aa\/5842701\/\">Recognition of ZnT8, Proinsulin, and Homologous MAP Peptides in Sardinian Children at Risk of T1D Precedes Detection of Classical Islet Antibodies.<\/a><\/p>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>MAP is a pathogenic bacterium infecting livestock and is prevalent in dairy products.\u00a0 Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after &hellip; <a href=\"https:\/\/www.lifetein.com\/blog\/predicting-type-1-diabetes-in-children\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1919,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[4],"tags":[62,27],"class_list":["post-288","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis","tag-diabetes","tag-peptide"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"MAP is a pathogenic bacterium infecting livestock and found prevalent in dairy products. Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after being exposed to MAP in dairy foods, and generating antibodies against MAP, and might subsequently develop type I diabetes. \" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"LifeTein Peptide\"\/>\n\t<meta name=\"google-site-verification\" content=\"xKDW6DUiGuZ6nwglNeWlVWTgzTtMPzas13ROL63ytTc\" \/>\n\t<meta name=\"msvalidate.01\" content=\"5B15601215D876311F84CFEFB0F72F18\" \/>\n\t<meta name=\"keywords\" content=\"diabetes peptide,diabetes,peptide\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.lifetein.com\/blog\/predicting-type-1-diabetes-in-children\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.10\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"LifeTein Peptide Synthesis Blog\" \/>\n\t\t<meta property=\"og:type\" content=\"activity\" \/>\n\t\t<meta property=\"og:title\" content=\"Predicting type 1 diabetes in children | LifeTein Peptide Blog\" \/>\n\t\t<meta property=\"og:description\" content=\"MAP is a pathogenic bacterium infecting livestock and found prevalent in dairy products. Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after being exposed to MAP in dairy foods, and generating antibodies against MAP, and might subsequently develop type I diabetes. \" \/>\n\t\t<meta property=\"og:url\" content=\"https:\/\/www.lifetein.com\/blog\/predicting-type-1-diabetes-in-children\/\" \/>\n\t\t<meta property=\"fb:admins\" content=\"233983946638783\" \/>\n\t\t<meta property=\"og:image\" content=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg\" \/>\n\t\t<meta property=\"og:image:secure_url\" content=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg\" \/>\n\t\t<meta name=\"twitter:card\" content=\"summary\" \/>\n\t\t<meta name=\"twitter:site\" content=\"@lifetein\" \/>\n\t\t<meta name=\"twitter:title\" content=\"Predicting type 1 diabetes in children | LifeTein Peptide Blog\" \/>\n\t\t<meta name=\"twitter:description\" content=\"MAP is a pathogenic bacterium infecting livestock and found prevalent in dairy products. Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after being exposed to MAP in dairy foods, and generating antibodies against MAP, and might subsequently develop type I diabetes. \" \/>\n\t\t<meta name=\"twitter:creator\" content=\"@lifetein\" \/>\n\t\t<meta name=\"twitter:image\" content=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg\" \/>\n\t\t<!-- All in One SEO -->\n\n","aioseo_head_json":{"title":"Predicting type 1 diabetes in children | LifeTein Peptide Blog","description":"MAP is a pathogenic bacterium infecting livestock and found prevalent in dairy products. Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after being exposed to MAP in dairy foods, and generating antibodies against MAP, and might subsequently develop type I diabetes. ","canonical_url":"https:\/\/www.lifetein.com\/blog\/predicting-type-1-diabetes-in-children\/","robots":"max-image-preview:large","keywords":"diabetes peptide,diabetes,peptide","webmasterTools":{"google-site-verification":"xKDW6DUiGuZ6nwglNeWlVWTgzTtMPzas13ROL63ytTc","msvalidate.01":"5B15601215D876311F84CFEFB0F72F18","miscellaneous":""},"schema":null,"og:locale":"en_US","og:site_name":"LifeTein Peptide Synthesis Blog","og:type":"activity","og:title":"Predicting type 1 diabetes in children | LifeTein Peptide Blog","og:description":"MAP is a pathogenic bacterium infecting livestock and found prevalent in dairy products. 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Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after being exposed to MAP in dairy foods, and generating antibodies against MAP, and might subsequently develop type I diabetes. ","twitter:creator":"@lifetein","twitter:image":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2020\/02\/LifeTein-Blog1-2-scaled.jpg"},"aioseo_meta_data":{"post_id":"288","title":"Predicting type 1 diabetes in children | #site_title","description":"MAP is a pathogenic bacterium infecting livestock and found prevalent in dairy products.\u00a0 Because some of its proteins are sequentially homologous to human zinc transporter 8 (ZnT8) protein and proinsulin (PI), children could develop autoimmunity against ZnT8 and PI after being exposed to MAP in dairy foods, and generating antibodies against MAP, and might subsequently develop type I diabetes.\u00a0","keywords":[{"label":"diabetes peptide","value":"diabetes 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22:27:49","updated":"2025-06-18 02:41:15"},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.lifetein.com\/blog\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.lifetein.com\/blog\/category\/peptide_synthesis\/\" title=\"Peptide\">Peptide<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tPredicting type 1 diabetes in children\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/www.lifetein.com\/blog"},{"label":"Peptide","link":"https:\/\/www.lifetein.com\/blog\/category\/peptide_synthesis\/"},{"label":"Predicting type 1 diabetes in 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