A tumor-penetrating peptide, iRGD, was synthesized by LifeTein. It was found that iRGD improves tumor-specific penetration of intraperitoneal compounds and enhances intraperitoneal chemotherapy (IPC) in mice. This penetration was tumor-specific. When the FITC was attached to iRGD and mixed with nanoparticles, the mixture could penetrate into fresh human peritoneal metastasis explants. The evidence proved that the LifeTein iRGD enhanced intratumoral entry. The intraperitoneal iRGD co-administration is a simple and effective strategy to facilitate tumor detection and potential application for therapeutic improvement.<\/p>\n
A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis, Journal of Controlled Release, Volume 212, 28 August 2015, Pages 59\u201369<\/a><\/p>\n Peptide Synthesis Home Page<\/a><\/p>\n\n\n Our Services:<\/p>\n\n\n\n COVID-19 Services & Products<\/a><\/p>\n\n\n\n Custom Antibody Services<\/a><\/p>\n\n\n\n Rush Peptide Synthesis<\/a><\/p>\n\n\n\n Peptide Nucleic Acids (PNAs)<\/a><\/p>\n\n\n\n Custom Peptide Synthesis Services<\/a><\/p>\n\n\n\n Gene Synthesis Service<\/a><\/p>\n\n\n\n Custom Chemical Synthesis<\/a><\/p>\n\n\n\n Other Posts:<\/p>\n\n\n\n Nanoparticles Get Help from Cell-Permeable Peptides<\/a><\/p>\n\n\n\n Predicting type 1 diabetes in children<\/a><\/p>\n\n\n\n Improving Antibody Therapy For Colorectal Cancer<\/a><\/p>\n\n\n\n To Make Simpler and Better Biosensors<\/a><\/p>\n\n\n\n A New Patent Using Peptides<\/a><\/p>\n\n\n\n <\/p>\n","protected":false},"excerpt":{"rendered":" A tumor-penetrating peptide, iRGD, was synthesized by LifeTein. It was found that iRGD improves tumor-specific penetration of intraperitoneal compounds and enhances intraperitoneal chemotherapy (IPC) in mice. This penetration was tumor-specific. When the FITC was attached to iRGD and mixed with … Continue reading