{"id":280,"date":"2015-07-13T11:28:39","date_gmt":"2015-07-13T15:28:39","guid":{"rendered":"http:\/\/www.lifetein.com\/blog\/?p=280"},"modified":"2024-11-16T22:40:00","modified_gmt":"2024-11-17T03:40:00","slug":"tumor-penetrating-peptide-irgd","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/tumor-penetrating-peptide-irgd\/","title":{"rendered":"Innovative Tumor-Permeable Peptide iRGD Targets Cancer with Precision"},"content":{"rendered":"<p>A tumor-penetrating peptide, iRGD, was synthesized by LifeTein. It was found that iRGD improves tumor-specific penetration of intraperitoneal compounds and enhances intraperitoneal chemotherapy (IPC) in mice. This penetration was tumor-specific. When the FITC was attached to iRGD and mixed with nanoparticles, the mixture could penetrate into fresh human peritoneal metastasis explants. The evidence proved that the LifeTein iRGD enhanced intratumoral entry. The intraperitoneal iRGD co-administration is a simple and effective strategy to facilitate tumor detection and potential application for therapeutic improvement.<\/p>\n<h2 style=\"text-align: center;\">LifeTein&#8217;s Peptide: iRGD<\/h2>\n<p><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0168365915006161\" target=\"_blank\" rel=\"noopener\">A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis, Journal of Controlled Release, Volume 212, 28 August 2015, Pages 59\u201369<\/a><\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/www.lifetein.com\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">Peptide Synthesis Home Page<\/a><\/p>\n\n\n<p class=\"wp-block-paragraph\">Our Services:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/peptide-product\/covid19products-c-64.html\" target=\"_blank\" rel=\"noreferrer noopener\">COVID-19 Services &amp; Products<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/antibody_services.html\" target=\"_blank\" rel=\"noreferrer noopener\">Custom Antibody Services<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/Rush-Peptide-Synthesis-Service.html\" target=\"_blank\" rel=\"noreferrer noopener\">Rush Peptide Synthesis<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/Peptide-Nucleic-Acid.html\" target=\"_blank\" rel=\"noreferrer noopener\">Peptide Nucleic Acids (PNAs)<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/peptide_synthesis_services.html\" target=\"_blank\" rel=\"noreferrer noopener\">Custom Peptide Synthesis Services<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/protein-expression-service.html\" target=\"_blank\" rel=\"noreferrer noopener\">Gene Synthesis Service<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/custom_chemical_synthesis.html\" target=\"_blank\" rel=\"noreferrer noopener\">Custom Chemical Synthesis<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Other Posts:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/blog\/nanoparticles-get-help-from-cell-penetrating-peptides\/\" target=\"_blank\" rel=\"noreferrer noopener\">Nanoparticles Get Help from Cell-Permeable Peptides<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/blog\/predicting-type-1-diabetes-in-children\/\" target=\"_blank\" rel=\"noreferrer noopener\">Predicting type 1 diabetes in children<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/blog\/improving-antibody-therapy-for-colorectal-cancer\/\" target=\"_blank\" rel=\"noreferrer noopener\">Improving Antibody Therapy For Colorectal Cancer<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/blog\/to-make-simpler-and-better-biosensors\/\" target=\"_blank\" rel=\"noreferrer noopener\">To Make Simpler and Better Biosensors<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.lifetein.com\/blog\/a-new-patent-using-peptides\/\" target=\"_blank\" rel=\"noreferrer noopener\">A New Patent Using Peptides<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A tumor-penetrating peptide, iRGD, was synthesized by LifeTein. It was found that iRGD improves tumor-specific penetration of intraperitoneal compounds and enhances intraperitoneal chemotherapy (IPC) in mice. This penetration was tumor-specific. When the FITC was attached to iRGD and mixed with &hellip; <a href=\"https:\/\/www.lifetein.com\/blog\/tumor-penetrating-peptide-irgd\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1785,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[3,54,16],"class_list":["post-280","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis","tag-cell-penetrating-peptide-synthesis","tag-tumor-peptide","tag-tumor-associated-antigens"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"A tumor-penetrating peptide iRGD by LifeTein was found to target 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22:27:49","updated":"2025-06-18 02:41:15"},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.lifetein.com\/blog\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.lifetein.com\/blog\/category\/peptide_synthesis\/\" title=\"Peptide\">Peptide<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tInnovative Tumor-Permeable Peptide iRGD Targets Cancer with Precision\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/www.lifetein.com\/blog"},{"label":"Peptide","link":"https:\/\/www.lifetein.com\/blog\/category\/peptide_synthesis\/"},{"label":"Innovative Tumor-Permeable Peptide iRGD Targets Cancer with 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