{"id":186,"date":"2013-10-18T14:04:31","date_gmt":"2013-10-18T18:04:31","guid":{"rendered":"http:\/\/www.lifetein.com\/blog\/?p=186"},"modified":"2024-11-16T22:37:38","modified_gmt":"2024-11-17T03:37:38","slug":"phospho-specific-antibodies-lifetein-published-nature","status":"publish","type":"post","link":"https:\/\/www.lifetein.com\/blog\/phospho-specific-antibodies-lifetein-published-nature\/","title":{"rendered":"Phospho-specific antibodies by LifeTein published in Nature"},"content":{"rendered":"

Jia Shen. et al. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature<\/strong> 497, 383\u2013387 (16 May 2013), doi:10.1038\/nature12080<\/a> LifeTein helped designed and synthesized a series of phosphorylated peptide<\/a>s. Then the peptides were used for phospho-specific antibody<\/a> productions. The phospo-specific antibodies by LifeTein were confirmed to react with the epidermal growth factor receptor (EGFR). The Hung’s lab showed that AGO2-Y393 phosphorylation mediates EGFR-enhanced cell survival and invasiveness under hypoxia. These findings suggest that modulation of miRNA biogenesis is important for stress response in tumour cells. … The following peptides were chemically synthesized for antibody production<\/a> in mice (Lifetein<\/strong>\u00a0Conc.), Elisa verification (Lifetein<\/strong>Conc.) and peptide competition assay in immunohistochemistry (IHC)…<\/em> Supplementary information<\/a><\/p>\n

Phospho-Specific Antibodies by LifeTein<\/h2>\n\n

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Jia Shen. et al. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature 497, 383\u2013387 (16 May 2013), doi:10.1038\/nature12080 LifeTein helped designed and synthesized a series of phosphorylated peptides. Then the peptides were used for phospho-specific … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1920,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[30,31,3,27],"class_list":["post-186","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-peptide_synthesis","tag-antibody","tag-antibody-production","tag-cell-penetrating-peptide-synthesis","tag-peptide"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/186","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/comments?post=186"}],"version-history":[{"count":0,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/186\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media\/1920"}],"wp:attachment":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media?parent=186"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/categories?post=186"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/tags?post=186"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}